Applications
2-Chlorophenylacetic Acid is used in the synthesis of anti-proliferatives and anticancer agents. Also used in the synthesis of 4-phenoxybenzamide analogues as opiod receptor antagonists.
 
Description
Ortho Chloro Phenyl Acetic Acid is an organic compound with a chloro-substituted phenyl ring and a carboxylic acid group in the ortho position, commonly used as an intermediate in pharmaceutical and chemical synthesis.
 
Preparation
In the 2000ml four-hole boiling flask, drop into 98% vitriol oil 707g (7.07mol), water 471g, under 90～130 ℃, the adjacent chlorobenzene acetonitrile 693g (4.53mol) of slow dropping 99.0%, after the insulation reaction 1 hour, steam the water of about 260g, 130～150 ℃ again insulation reaction stopped in 3 hours ( …
 
Chemical Properties
Ortho Chloro Phenyl Acetic Acid exhibits chemical properties related to its aromatic structure, containing a chlorine atom and a carboxylic acid functional group, often used in organic synthesis and pharmaceutical production.
 
Definition
Ortho Chloro Phenyl Acetic Acid is an organic compound characterized by a phenyl ring with a chlorine atom and a carboxylic acid functional group in the ortho position, commonly used as an intermediate in chemical and pharmaceutical synthesis.
Chemical formula   C8H7ClO2
Molar mass            170.59 grams per mole
Density         1.2315 (rough estimate)
Boiling point          145°C 5mm
Technical Analysis
Specification        Typical Values
Colour (APHA)         White to light yellow
CAS NO.            2444-36-2
Solubility     slightly soluble in Chloroform, DMSO , Methanol.
4-chlorophenylacetic acid is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-chlorophenyl group.