N-Hydroxysuccinimide (NHS) is an organic compound with the formula (CH2CO)2NOH. It is a white solid that is used as a reagent for preparing active esters in peptide synthesis. It can be synthesized by heating succinic anhydride with hydroxylamine or hydroxylamine hydrochloride.
Cross-Linking Reagent: NHS is frequently used in conjunction with N-ethyl-N'-(3-dimethylaminopropyl) carbodiimide (EDC) to form NHS esters. These esters are highly reactive and can be used to link proteins, peptides, or other molecules to surfaces or to each other.
Bioconjugation: In biochemistry, NHS esters are valuable for labeling and tagging biomolecules.
Stability and Reactivity: NHS esters are more stable than their unmodified counterparts and are typically easier to handle.
Applications: Beyond bioconjugation, NHS is used in a variety of research and clinical settings, including in the synthesis of materials for drug delivery systems, development of biomaterials, and in the creation of antibody-conjugate therapies.
Sihauli Chemicals is one of the leading N – Hydroxy Succinimide Manufacturer and Exporter form India. Sihauli Chemicals SupplyN – Hydroxy Succinimide to Asia, Africa, Europe, North & South America and Oceania.
Our Global Presense:Asia: Bangladesh, Burma (Myanmar), China, Hong Kong (UK), Indonesia, Iran, Israel, Japan, Jordan, Kampuchea (Cambodia), Kuwait, Laos, Lebanon, Macao (Portuguese), Malaysia, Maldives, Mongolia, Nepal, Oman, Philippines, Qatar, Saudi Arabia, Singapore, South Korea, Sri Lanka, Taiwan, Thailand, Turkey, United Arab Emirates, Vietnam.
Europe: Albania, Andorra, Austria, Belgium, Bulgaria, Cyprus, Czechoslovakia, Denmark, Finland, France, German Democratic Republic, Gibraltar, Greece, Hungary, Iceland, Ireland, Italy, Liechtenstein, Luxembourg, Malta, Monaco, Netherlands, Norway, Poland, Portugal, Romania, San Marino, Spain, Sweden, Switzerland, United Kingdom, U.S.S.R., Yugoslavia. Africa: Algeria, Angola, Egypt, Ethiopia, Gabon, Ghana, Kenya, Liberia, Libya, Madagascar, Mauritius, Morocco, Mozambique, Namibia, Nigeria, Reunion (France), Seychelles, Somalia, South Africa, Sudan, Tanzania, Tunisia, Uganda, Zambia, Zimbabwe.
North America: Bahamas, Barbados, Bermuda, British Virgin Islands, Canada, Costa Rica, Cuba, Dominica, El Salvador, Greenland (Denmark), Grenada, Guatemala, Haiti, Honduras, Jamaica, Martinique, Mexico, Montserrat, Nicaragua, Panama, Puerto Rico (USA), St. Vincent & the Grenadines, Trinidad & Tobago, USA, Virgin Islands.
South America: Argentina, Bolivia, Brazil, Chile, Colombia, Ecuador, French Guiana, Guyana, Paraguay, Peru, Venezuela.
Oceania: Australia, New Zealand, Solomon Islands, Wallis & Futuna Islands (France).
N – Hydroxy Succinimide
Molar Mass 115.09 g/mol CAS No 6066-82-6 Formula C4H5NO3 Melting Point 95 Deg C N-Hydroxysuccinimide (NHS) is an organic compound with the formula C4H5NO3. Being slightly acidic, it is an irritant to skin, eyes and mucous membranes.






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