Applications
For example, in a painkiller, the active ingredient relieves pain. In the OTC drug Crocin, the API is paracetamol. Only a small amount of the API is required to produce the effect and so the medicine contains only the required amount of the API. Some drugs contain multiple APIs to treat varied symptoms.
 
Description
Active pharmaceutical ingredients (APIs) are the active components in a pharmaceutical drug that produce the required effect on the body to treat a condition. APIs are produced by processing chemical compounds. In a biologic drug, the active ingredient is known as a bulk process intermediate (BPI).
 
Preparation
Developing and producing Active Pharmaceutical Ingredients (APIs) includes various processing steps, such as reaction, crystallization, separation and purification, filter cake washing, solvent swap, and solvent exchange.
 
Chemical Properties
The physicochemical properties of APIs, especially solubility, stability, in vitro dissolution and bioavailability, are of critical importance to pre-formulation as they will not only affect the choice and design of formulation, but also influence the performance of the dosage forms.
 
Definition
APIs (Active Pharmaceutical Ingredients) are the biologically active components of a pharmaceutical drug responsible for its therapeutic effects, produced through chemical or biological synthesis.