Applications
Piperidine is used as a raw material for pharmaceuticals, agrochemicals, rubber chemicals, surface-active agents and other organic chemicals. A review on catalytic hydrogenation of pyridine was published in Advances in Catalysis.
 
Description
It is a colorless liquid with an odor described as objectionable, and typical of amines. The name comes from the genus name Piper, which is the Latin word for pepper.
 
Preparation
Piperidine is commonly manufactured by hydrogenation of pyridine over Pt, Pd or Raney-Ni catalyst in a liquid-phase reaction. Complete saturation of the pyridine ring can be achieved by nickel-aluminium alloy in 0.5 M KOH at rt with yields of 51–90%. The reduction with sodium and alcohol was also reported.
 
Chemical Properties
Piperidine is a heterocyclic organic compound known for its basicity and versatile applications in organic synthesis, particularly as a catalyst and a precursor to pharmaceuticals and agrochemicals.
 
Definition
Piperidine is a cyclic organic compound containing a six-membered ring with one nitrogen atom, commonly used as a building block in organic chemistry and found in various pharmaceuticals and agrochemicals.