Pentapeptide-18 is a synthetic peptide composed of five amino acids (pentapeptide), widely used in cosmetic formulations for anti-aging and wrinkle-reduction purposes. It is classified as a biomimetic peptide, designed to mimic natural signaling molecules in the skin that regulate muscle contraction.
This peptide works by modulating neuromuscular signals in the skin, helping to relax facial micro-muscle contractions that contribute to dynamic wrinkles, such as crow’s feet and forehead lines. When combined with other peptides like Acetyl Hexapeptide-8, Pentapeptide-18 can provide synergistic wrinkle-reducing effects, improving skin smoothness and firmness.
 
Applications: Anti-aging creams and serums Eye creams targeting crow’s feet and fine lines
Appearance:  White to off-white powder
Solubility:  Soluble in water and glycols
pH Range:  Typically stable in pH 4.0 – 7.5
Chemical Formula: C₂₈H₄₈N₈O₁₀
Cas. No: 616204-22-9