Applications
Niacin (nicotinic acid) is used to prevent and treat niacin deficiency (pellagra). Niacin deficiency may result from certain medical conditions (such as alcohol abuse, malabsorption syndrome, Hartnup disease), poor diet, or long-term use of certain medications (such as isoniazid).
 
Description
NA is the acid form of niacin. It is used in the clinic for the management of hyperlipidemia. Daily intake of 1–3 g has been reported to lower blood triglyceride levels and low-density lipoproteins (LDLs) and increase plasma levels of high-density lipoprotein (HDL) [11,12].
 
Preparation
Industrially, nicotinic acid is produced mainly by oxidation of 5-ethyl-2-methylpyridine with nitric acid. One of the by-products of the process is nitrous oxide, a gas that is difficult to recycle and manage, with a greenhouse effect 300 times stronger than CO2.
 
Chemical Properties
Nicotinic acid, also known as niacin or vitamin B3, is a white crystal or crystalline powder, odorless or has a slight odor, slight sour taste. Melting point is 234-237℃. Easily soluble in hot water, hot ethanol, alkaline water, propylene glycol, and chloroform.
 
Definition
Nicotinic acid, also known as niacin or vitamin B3, is an organic compound essential for metabolism and a precursor for coenzymes involved in energy production.