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Di-Tert-Butyl Dicarbonate
Di-tert-butyl dicarbonate is a reagent used for the introduction of BOC protecting group. It plays an important role in the preparation of 6-acetyl-1,2,3,4-tetrahydropyridine by reacting with 2-piperidone. It serves as a protecting group used in solid phase peptide synthesis.

Di-Tert-Butyl Dicarbonate

₹1,150.00Price
Quantity
  • Physical State Powder
    Usage Industrial
    Grade Standard Technical Grade

    CERTIFICATE OF ANALYSIS
    PRODUCT NAMEDI-TERT-BUTYL DICARBONATE

    INFORMATION OF DI-TERI-BUTYL DICARBONATE-Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis.[1] This carbonate ester reacts with amines to give N–tert-butoxycarbonyl or so-called Boc derivatives. These derivatives do not behave as amines, which allows certain subsequent transformations to occur that would have otherwise affected the amine functional group. The Boc can later be removed from the amine using acids. Thus, Boc serves as a protective group, for instance in solid phase peptide synthesis. It is unreactive to most bases and nucleophiles, allowing for an orthogonal Fluorenylmethyloxycarbonyl chloride (FMOC-Cl) protection.

    • CAS NO24424-99-5
    • FORMULAC10H18O5
    • MOLAR MASS218.25 gmol1
    • APPEARANCEcolourless solid
    • DENSITY0.95 gcm3
    • MELTING POINT22 to 24 Degree

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