Acetyl Dipeptide-1 Cetyl Ester is a synthetic peptide derivative commonly used in cosmetic formulations for its soothing, anti-stress, and anti-aging effects. It is composed of a dipeptide (two amino acids) linked to an acetyl and a cetyl ester group, which enhances its stability and allows better penetration into the skin.
This peptide works by modulating neuropeptides in the skin, helping to reduce skin sensitivity, irritation, and the visible effects of stress on the skin, such as redness or tightness. Additionally, it has moisturizing properties and can help improve skin barrier function, promoting a healthier, more resilient skin surface.
It is widely used in serums, creams, eye treatments, and after-sun products. Its gentle, non-irritating nature makes it suitable for all skin types, including sensitive skin, and it is especially valuable in formulations designed to calm stressed or reactive skin.
 
Applications: Used in cosmetic formulations for anti-aging, skin-soothing, and anti-stress purposes. Commonly included in serums, creams, eye treatments, after-sun products, and sensitive skin formulations to reduce irritation, redness, and signs of stress while improving skin barrier function.
Appearance:  White to off-white waxy or powdery solid
Solubility:  Soluble in oils, esters, and some organic solvents; slightly dispersible in water
pH Range: Typically stable in formulations with pH 4.0 – 7.0
Chemical Formula: C₂₀H₄₀N₂O₄
Cas. No: 1224693-54-0